Helicobacter pylori exposure linked to one in five cases of bowel cancer
Researchers found the microbe was linked to a 1.6-fold higher bowel cancer risk, with lower estimates in cohort-based studies.
- Published in eGastroenterology on Tuesday, a new exploratory study suggests exposure to the stomach microbe Helicobacter pylori may be associated with more than 1 in 5, or 22%, of bowel cancer cases worldwide.
- Gastroenterologist Iago Rodríguez-Lago noted the research uses a mathematical model rather than clinical trials, emphasizing that an association between the bacterium and cancer does not prove the infection causes these tumors.
- Data quality significantly impacts findings; when researchers restricted analysis to the highest-quality studies, the estimated link dropped from 22% to about one in nine cases, with a wider margin of error.
- Stratified by region, the Western Pacific and Mongolia showed the highest potential links at 25% and 36% respectively, while China recorded the highest absolute number of cases linked to exposure: 619.
- Researchers cautioned that large-scale Helicobacter eradication raises antibiotic resistance concerns, noting that observational data suggests eradication therapy only reduced disease risk after more than 10 years of follow-up.
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Common Stomach Bacteria Linked To 1 In 5 Bowel Cancer Cases In Global Analysis
An illustration of H pylori bacterium.Helicobacter pylori (H pylori), a common bacteria that can infect the stomach, has been linked to more than one in five bowel cancer cases worldwide, according to a new analysis. The bacteria has already been associated with stomach cancer in some individuals. Now, research suggests exposure might also be linked with up to a fifth of bowel cancer cases, too.And those born in more recent decades may be more a…
Helicobacter pylori exposure linked to one in five cases of bowel cancer
Exposure to the stomach microbe Helicobacter pylori may be associated with more than 1 in 5 cases of bowel cancer worldwide, suggests an exploratory risk attribution study, published in the open access journal eGastroenterology.
The Independent
New study finds link between common stomach bug exposure and bowel cancer
And using data from 43 studies, which involved more than 48 million people, scientists estimated that 22 per cent of bowel cancer cases worldwide are potentially related to H. pylori exposure
Helicobacter pylori inhabits the lining of the stomach, and is generally not accompanied by complaints, although it can lead to gastritis, increased secretion of stomach acid, and in some cases, as new research claims, to colon cancer.
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