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GLP-1s Don’t Work for Everyone. Scientists Finally Figured Out Why.

Summary by Men's Health
New genetic research finds that people with the PAM gene variant p.S539W have a harder time processing the GLP-1 hormone and may require alternative medications for weight loss and blood sugar management.

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Men's HealthMen's Health
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GLP-1s Don’t Work for Everyone. Scientists Finally Figured Out Why.

New genetic research finds that people with the PAM gene variant p.S539W have a harder time processing the GLP-1 hormone and may require alternative medications for weight loss and blood sugar management.

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Men's Health broke the news on Wednesday, May 6, 2026.
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