It Takes Two: Genes ATP13A2 and GBA1 Interact to Drive Neurodegeneration

It takes two: Genes ATP13A2 and GBA1 interact to drive neurodegeneration

Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease, affecting more than 10 million people worldwide. People with this condition may experience tremors, limb stiffness, gait and balance problems and move slowly, like when buttoning a shirt or walking. These symptoms happen because certain brain cells die over time. Although scientists have known some of the factors that raise a person's risk, th…

Genetic Duo: ATP13A2 and GBA1 Interactions Fuel Neurodegeneration

Parkinson’s disease (PD) ranks as the second most prevalent neurodegenerative disorder following Alzheimer’s disease, impacting more than 10 million individuals globally. The condition manifests through various symptoms such as tremors, rigidity in limbs, impaired gait, and difficulties with balance, resulting in a progressively slowed movement characteristic of this debilitating illness. These diverse manifestations arise from the gradual death…