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Gene Test Can Predict Breast Cancer Risk For Women Diagnosed With Abnormal Cells: study

A study by King's College London shows the 313-SNP polygenic risk score doubles invasive breast cancer risk after DCIS and LCIS, aiding personalized treatment decisions.

  • Women diagnosed with abnormal breast cells who scored high on a genetic blood test were twice as likely to develop breast cancer, a study found.
  • For women with ductal carcinoma in situ , high PRS313 scores were associated with increased risk of cancer in the opposite breast.
  • For those with lobular carcinoma in situ , higher PRS313 scores correlated with higher risk of cancer in the same breast where abnormal cells were found.
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Gene Test Can Predict Breast Cancer Risk For Women Diagnosed With Abnormal Cells

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Medical Xpress broke the news in on Wednesday, October 1, 2025.
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