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Gene Test Can Predict Breast Cancer Risk For Women Diagnosed With Abnormal Cells: study
A study by King's College London shows the 313-SNP polygenic risk score doubles invasive breast cancer risk after DCIS and LCIS, aiding personalized treatment decisions.
- Women diagnosed with abnormal breast cells who scored high on a genetic blood test were twice as likely to develop breast cancer, a study found.
- For women with ductal carcinoma in situ , high PRS313 scores were associated with increased risk of cancer in the opposite breast.
- For those with lobular carcinoma in situ , higher PRS313 scores correlated with higher risk of cancer in the same breast where abnormal cells were found.
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A polygenic risk score may predict future breast cancer in patients with early-stage diagnoses
A retrospective study found that the 313-SNP breast cancer polygenic risk score (PRS313) blood test could predict future incidents of breast cancer in women diagnosed with ductal carcinoma in situ (DCIS) or lobular carcinoma in situ (LCIS).
Polygenic Risk Score Predicts Which Lesions Will Become Breast Cancer
Researchers at King’s College London have shown that an existing genetic test for breast cancer can also predict future breast cancer in women with ductal carcinoma in situ (DCIS) or lobular carcinoma in situ (LCIS), two conditions characterized by lesions in breast tissue that can progress into breast cancer. Results of the study, published in Cancer Epidemiology, Biomarker & Prevention, show early potential for this genetic test to inform a mo…
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Leaning Left4Leaning Right5Center10Last UpdatedBias Distribution53% Center
Bias Distribution
- 53% of the sources are Center
53% Center
L 21%
C 53%
R 26%
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