Lab-Grown Brain Tissue Hits Five Years: Cells That Remember Time
Researchers kept human brain organoids alive for over five years, showing they followed human developmental timelines and could improve disease and drug studies.
4 Articles
4 Articles
Lab-Grown Brain Tissue Hits Five Years: Cells That Remember Time
Paola Arlotta walked into her Harvard lab one day a couple of years ago and got a surprise. Two junior scientists, Irene Faravelli and Noelia Antón-Bolaños, stood there with images from some very old experiments. They had analyzed brain organoids the team had kept alive far longer than anyone expected. “You analyzed them?” Arlotta exclaimed, according to a STAT report. She was pleased. The courage paid off. Those organoids didn’t just sit there.…
Using stem cells, a research team has succeeded in growing human mini-brains in Petri dishes for five years, with the nervous tissue eventually developing like real human brains.
Five-Year Brain Organoids Reveal New Insights Into Human Development
The human brain continues to develop for two decades. To study this prolonged process, researchers have traditionally relied on donated human brain tissue and animal models, both of which have limitations: donated tissue provides snapshots of brain development, and animal brains differ from the human brain in cell-type composition and timing of development. Despite their increasing utility, organoids have proven challenging to maintain over long…
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