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Newcastle vs. Arsenal Prediction, Odds, Start Time: 2025 Premier League Picks for Sunday, Sept. 28

On Sunday, Newcastle United host Arsenal at St James' Park with kick-off at 4:30 pm BST, and DraftKings lists Arsenal as +115 favorites while Newcastle are +250 underdogs.
Newcastle's defensive strength sets the tone ahead of the match as they rank third with 0.6 goals conceded per game and recent success over Arsenal at St James' Park.
Eddie Howe can alter his XI as returning players come back into contention with Anthony Gordon, winger, available after suspension and Sven Botman, defender, back, while Nick Woltemade, No 27 forward, leads the line and Will Osula, Carabao Cup standout, likely starts.
A positive result has immediate table implications as Arsenal can cut their five-point deficit to two, while Newcastle United can consolidate at home against a top rival at St James' Park.
Tactical bravery — including dropping a recent midfield three — is being urged for Arsenal, with pundits Martin Keown and Ashley Williams calling Sunday a must-win and Arteta expected to make three changes.

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