Study Suggests Hormone Replacement Therapy May Reduce Alzheimer’s Risk
Researchers said HRT users had a 16% lower dementia risk, with the biggest benefit seen after surgical menopause and in women with APOE4 variants.
- A new study tracking 183,450 postmenopausal women over 13.3 years found HRT linked to a 10% lower likelihood of dementia and 16% lower risk of Alzheimer's disease among users.
- The researchers support the "critical window" hypothesis, suggesting HRT may be more beneficial when initiated closer to the menopausal transition rather than later in life.
- Women who underwent surgical menopause saw a 26% lower risk of developing dementia, while those who began HRT between ages 46 and 56 experienced the greatest reduction in risk.
- David Llewellyn from the Exeter Medical School said these results represent a "significant step forward," noting that associations between HRT use and dementia were stronger in women carrying the APOE4 gene variant.
- Collis from the BBSRC added that findings suggest HRT could have greater protective benefits for specific groups, offering new insights into how menopause timing may influence future dementia risk.
45 Articles
45 Articles
HRT Linked to Lower Dementia Risk in Large UK Study
Share Post Share Email Hormone replacement therapy (HRT) may reduce the risk of dementia, particularly for certain groups of women – according to a study from the University of East Anglia and the University of Exeter. Researchers followed more than 180,000 postmenopausal women in the UK for this, the largest study of its kind to date. They found that women who had used HRT had a 16 per cent lower risk of developing Alzheimer’s (the main form of…
Estrogen Therapy Linked to Lower Alzheimer’s Risk
A form of hormone therapy used by many women after menopause may be linked to a lower risk of Alzheimer’s disease, according to a large study from Stanford Medicine. The strongest results were seen in women who used estrogen without the hormone progestin. Menopause happens when the ovaries greatly reduce their production of hormones such […] The post Estrogen Therapy Linked to Lower Alzheimer’s Risk appeared first on Knowridge Science Report.
Coverage Details
Bias Distribution
- 57% of the sources are Center
Factuality
To view factuality data please Upgrade to Premium
