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Engineered Rabies Virus Reveals How Psilocybin Reshapes Neural Pathways

Summary by The Debrief
Tracing neural circuits with a specially engineered rabies virus, researchers have found that psilocybin disrupts feedback loops associated with negative thought patterns. The findings, detailed in a recent study published in Cell, show how psilocybin reshapes connections across the brain, helping explain why a single dose can ease depression symptoms for weeks or even months. The research, led by Cornell University biomedical engineer Alex Kwan…

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The Debrief broke the news in on Wednesday, December 10, 2025.
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