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Pharmaceutical Giant to Invest $6B in Alabama Facility

Lilly will create 450 permanent jobs and 3,000 construction jobs to boost supply chain resilience and local economic activity, expecting $4 in economic output per dollar invested.

  • Eli Lilly and Company announced Tuesday it will invest more than $6 billion in a manufacturing facility at Greenbrier South industrial park, Huntsville, Alabama, with work starting in 2026 and completion in 2032.
  • The company said the investment is part of a broader push to onshore API production, following a February plan to spend at least $27 billion on four U.S. plants.
  • Lilly said production will include orforglipron and small-molecule synthetic and peptide ingredients while embedding machine learning, AI and digital automation for right-first-time execution.
  • The company said the project will create 450 permanent jobs, 3,000 construction jobs, and generate up to $4 in local economic activity per dollar invested, boosting Huntsville's workforce.
  • Lilly said proximity to the HudsonAlpha Institute for Biotechnology and utilities, transportation, favorable zoning and incentives drove Huntsville site selection, but the press release warned of risks affecting costs and timing, and a forthcoming site announcement is expected in the coming weeks.
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The Business Journals broke the news in United States on Tuesday, December 9, 2025.
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