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Unseen Dangers: The Impact of PFAS on Birth Outcomes

University of Arizona study finds PFAS exposure through well water increases infant death risk by 191% and preterm birth risk by 168%, estimating $8 billion annual economic impact.

  • On Monday, a PNAS paper by University of Arizona researchers reported that PFAS in New Hampshire well water is linked to worse birth outcomes among more than 11,000 mothers near 41 sites.
  • Using a natural experiment, the team compared downstream and upstream wells and confirmed higher PFAS in downstream wells, as most PFAS remain in shallow soils near farms, industry and firefighting sites migrating slowly into groundwater.
  • Data show large relative risks among the smallest and earliest births, with downstream wells linked to a 180% greater chance of births under 2.2 pounds and a 168% higher preterm birth rate, adding about 607 and 466 such births per 100,000.
  • Economists on the team calculated annual societal costs of about $8 billion from birth-related harms, exceeding the $3.8 billion estimated annual utility cleanup cost under EPA cleanup rules, so the authors argue reproductive benefits could justify the rule.
  • Practical steps include home or utility activated carbon filtration, which can remove long-chain PFAS, and Guo said, `We would expect similar things happening in other states that have similar level of contamination,` especially Maine.
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Science Media Centre broke the news in London, United Kingdom on Monday, December 8, 2025.
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