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DNMT3A R882H Is Not Required for Disease Maintenance in Primary Human AML but Is Associated with Increased Leukemia Stem Cell Frequency

Summary by Stemwell Science News
The authors developed CRISPR-based methods to directly correct DNMT3AR882 mutations in leukemic cells obtained from patients. [Cancer Discovery] Abstract
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Stemwell Science NewsStemwell Science News

DNMT3A R882H Is Not Required for Disease Maintenance in Primary Human AML but Is Associated with Increased Leukemia Stem Cell Frequency

The authors developed CRISPR-based methods to directly correct DNMT3AR882 mutations in leukemic cells obtained from patients. [Cancer Discovery] Abstract

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Stemwell Science News broke the news in on Tuesday, February 3, 2026.
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