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College football picks against the spread: Penn State-UCLA and more

Experts favor Penn State by 25.5 points and Tulsa by 19.5 points in Week 6, highlighting defensive struggles and offensive strengths in key matchups.

Summary by Penn Live
After a loaded college football slate in Week 5, we’ve got plenty of intriguing games across the country in Week 6. Let’s make some betting predictions.

Bias Distribution

  • 50% of the sources lean Left, 50% of the sources are Center
50% Center

Factuality 

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Ownership

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Penn Live broke the news in Harrisburg, United States on Wednesday, October 1, 2025.
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