CNN: Blood Tests for Cancer Detection Show Promise but Still Have Limitations
The study found Galleri increased cancers detected through screening 6.5-fold, with nearly half of new cases found at stages 1 or 2.
- A new study published in Nature Medicine shows the Galleri blood test substantially increased cancer detection when added to standard screenings, identifying cancers that might otherwise have gone undetected until later stages.
- Developed by GRAIL, the Galleri test uses a machine-learning algorithm to examine chemical patterns in blood that distinguish cell-free DNA from healthy cells versus cancerous ones, screening for more than 50 different cancer types.
- Adding the test to standard clinical recommendations increased cancer detection 6.5-fold, with nearly three-quarters of newly found cancers diagnosed at stages 1 through 3, where curative treatment is often possible.
- FDA advisers voted Wednesday that the Galleri test is safe and effective for certain patients; Dr. Nima Nabavizadeh of OHSU said it "finds many of these cancers while they're still asymptomatic and localized, when cure is still possible."
- The test is not routinely covered by insurance and costs between $700 and $3,500 out of pocket. Nabavizadeh emphasized, "promise isn't proof," cautioning that rigorous trials must precede wider commercialization.
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4 Articles
PATHFINDER 2 findings advance multi-cancer early detection blood testing
A single blood draw that screens for more than 50 cancers substantially increased cancer detection when added to standard screening, identifying cancers that otherwise might have gone undetected until later stages, according to a new study from the Oregon Health & Science University Knight Cancer Institute.
A simple blood draw can check for cancer. But who should get one?
A blood draw can find DNA fragments from tumors and possibly flag the earliest whispers of more than 50 cancers. CNN’s Dr. Sanjay Gupta faced the decision about whether he should do it - and what was really at stake with the information he would gain.
Blood test detects more cancers when added to standard screening
A single blood draw that screens for more than 50 cancers substantially increased cancer detection when added to standard screening, identifying cancers that otherwise might have gone undetected until later stages, according to a new study from the Oregon Health & Science University Knight Cancer Institute.
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