Chemo-optogenetic tool uses vitamin B₁₂ and green light to precisely regulate cell communication

Chemo-optogenetic tool uses vitamin B₁₂ and green light to precisely regulate cell communication

Researchers at The Hong Kong University of Science and Technology (HKUST) have developed CarGAP, a chemo-optogenetic tool that uses vitamin B₁₂ and green light to precisely control gap junctions, the microscopic channels enabling direct cell-to-cell communication. This innovation allows on-demand closing and opening of these intercellular bridges, providing unprecedented spatiotemporal control over vital molecules and electrical signals. Demonst…

HKUST Engineers Develop CarGAP, a Vitamin B₁₂ and Light-Controlled Molecular Valve to Precisely Regulate Cell Communication | The Hong Kong University of Science and Technology

HKUST Engineers Develop CarGAP, a Vitamin B₁₂ and Light-Controlled Molecular Valve to Precisely Regulate Cell Communication Anonymous (not verified) Fri, 03/20/2026 - 15:35 Researchers at The Hong Kong University of Science and Technology (HKUST) have developed CarGAP, a groundbreaking chemo-optogenetic tool that uses vitamin B₁₂ and green light to precisely control gap junctions, the microscopic channels enabling direct cell-to-cell communicati…