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A phase III trial with 236 adults showed a chemo-free regimen of ponatinib plus blinatumomab improved event-free survival to 87% versus 71% with chemo, researchers reported.
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Chemotherapy-free regimen could be new standard in Ph+ acute lymphoblastic leukemia
ORLANDO — A chemotherapy-free regimen significantly improved outcomes compared with standard therapy for newly diagnosed Ph+ acute lymphoblastic leukemia, according to study results presented at ASH Annual Meeting and Exposition.Patients who received ponatinib (Iclusig, Takeda) and blinatumomab (Blincyto, Amgen) achieved higher rates of clinical hematologic remission and minimal residual
Chemotherapy-free combination treatment outperforms traditional regimens in patients with Ph+ ALL
A chemotherapy-free combination treatment outperformed a combination of targeted therapy and chemotherapy among patients with Ph+ acute lymphoblastic leukemia (ALL) in a new study.
·United States
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