Parkinson's Risk and Carbon Monoxide: What a New Study Found
Among 512,701 adults, never-smokers with exhaled carbon monoxide of 3 ppm or higher had about 30% lower Parkinson's risk, researchers found.
- On Tuesday, a study published in JAMA Neurology found non-smokers with higher exhaled carbon monoxide levels had approximately 30% lower Parkinson's risk, tracking 512,701 adults in the China Kadoorie Biobank for 12.1 years.
- Scientists have long observed an inverse relationship between smoking and Parkinson, often attributing protection to nicotine; this study challenges that assumption, suggesting carbon monoxide itself may be the key factor.
- Among non-smokers, exhaled carbon monoxide levels of 3 ppm or greater were associated with an approximately 30% lower risk of Parkinson, researcher Andri Iona reported, with higher levels showing a broad dose-dependent inverse relationship.
- Co-Author Clara Bueno Lopez, MSc, wrote, "For the first time, this study provides robust evidence in humans supporting a potentially protective role for CO in Parkinson's," offering a potential explanation for associations known for decades.
- An ongoing phase IIa trial is investigating the effects of the oral drug HBI-002 in patients with Parkinson, as researchers evaluate low-dose carbon monoxide as a potential therapeutic strategy.
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The toxic carbon monoxide from wood stoves and cigarettes appears to offer some protection against Parkinson's. American doctors are therefore already...
CO, a gas produced in the combustion of tobacco, also comes from stoves and stoves of coal or wood and is behind the so-called 'sweet death'. Those who exhaled more CO presented less risk of developing parkinson 12 years later.
Why is smoking linked to a lower risk of Parkinson's?
A link between carbon monoxide and Parkinson's disease may explain why smokers are at lower risk of developing the condition, according to international research. The team monitored the health of 512,701 Chinese adults over 12 years, including 1,131 people with Parkinson's and 2,949 with other neurodegenerative diseases. They investigated the impact of smoking using self-reported smoking frequency and measurements of carbon monoxide in breath—us…
Parkinson's Risk and Carbon Monoxide: What a New Study Found
(MedPage Today) -- Non-smokers with higher exhaled carbon monoxide (CO) levels had a lower risk of Parkinson's disease, a prospective study of more than 500,000 people in China showed. Among people who never smoked, exhaled CO levels of 3 ppm...
Women cross avenue in Beijing, China, on a day of heavy pollution. Research with more than 500,000 Chinese adults found association between higher levels of exhaled carbon monoxide and lower risk of Parkinson's disease. AP Photo/Andy Wong People who never smoked, but had higher levels of carbon monoxide in the exhaled air, had a lower risk of developing Parkinson's disease over about 12 years, shows a research with more than 500,000 adults in Ch…
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