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Brandon Aiyuk’s tenure with 49ers likely over after latest roster move: report

  • The San Francisco 49ers reclassified Brandon Aiyuk to reserve/left squad on Saturday, making him ineligible to return this season and effectively ending his year.
  • Brandon Aiyuk has missed the entire season while recovering from a severe knee injury, as he has not played since tearing his ACL, MCL and meniscus on October 20, 2024, and has not been seen at the 49ers facility in recent weeks.
  • According to a November 21 report, the Niners removed guaranteed money, wiping out a $24.935 million option bonus and earlier voiding roughly $27 million in 2026 guarantees.
  • The designation likely sets up an offseason split between the San Francisco 49ers and Aiyuk, with the club facing nearly $30 million in dead-money charges if they release him.
  • George Kittle said `At this point, it doesn't seem like he's coming back`, highlighting how Jauan Jennings is the only receiver with a touchdown this season, forcing personnel adjustments.
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49ers place Brandon Aiyuk on reserve list, ending his season and likely his tenure

The San Francisco 49ers have placed receiver Brandon Aiyuk on the reserve/left squad list, making him ineligible to return from a knee injury this season.

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NFLTradeRumors.co broke the news in on Saturday, December 13, 2025.
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