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AstraZeneca to invest $2 billion in Summit Therapeutics for cancer drug tie-up

  • On Monday, British drugmaker AstraZeneca announced a $2 billion investment in Summit Therapeutics to collaborate on clinical trials testing their cancer treatments together.
  • The partnership centers on ivonescimab, a next-generation cancer treatment Summit licensed from China's Akeso that simultaneously blocks PD-1 and VEGF to inhibit tumor growth.
  • AstraZeneca will purchase preferred shares at an equivalent price of $18.36 per share, representing an 18.6% premium, prompting Summit's shares to rise over 15% in extended trading.
  • Both firms will jointly fund clinical trials combining ivonescimab with AstraZeneca's Sone-Ve and other cancer medicines, with the transaction expected to close by the end of the week.
  • AstraZeneca executive vice president Susan Galbraith said combining ivonescimab with the company's antibody drug conjugates portfolio "could enable new regimens that raise the bar for patients with cancer.
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AstraZeneca invests £1.5bn into US firm Summit for cancer drug tie-up

The firms will collaborate on Summit’s experimental new medicine as well as researching how it could be combined with Astra’s treatments.

·London, United Kingdom
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Reuters broke the news in London, United Kingdom on Monday, September 28, 2026.
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