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Andreessen Horowitz's new $2.2 billion crypto fund is chasing stablecoins, DeFi, and the builders no one is watching

The firm is targeting stablecoins, payments and AI infrastructure as generalist investors shift toward artificial intelligence, with capital deployed over a decade.

  • On Tuesday, Andreessen Horowitz launched a $2.2 billion crypto fund called 'Crypto Fund 5,' targeting founders building durable products on blockchain infrastructure that persist beyond hype cycles.
  • Venture firms are shifting capital toward regulated, capital-intensive sectors where government relationships matter as much as technical insight, a pivot Coinbase CEO Brian Armstrong noted reflects the changing investment landscape.
  • Haun Ventures founder Katie Haun raised $1 billion for two new funds, targeting financial infrastructure for autonomous AI agents that require regulated money movement before they need better models.
  • Major payments companies including Stripe, Mastercard, PayPal, and Visa are developing infrastructure for autonomous AI agent transactions, reflecting industry consensus that agents require dedicated financial rails.
  • Paradigm, led by co-founder Matt Huang, raised $1.5 billion in February targeting the AI-crypto intersection, while Haun bets that focused firms owning this financial infrastructure category can outperform generalists.
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PYMNTS.com broke the news on Monday, May 4, 2026.
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