New Blood Test Spots One of Deadliest Cancers at Its Earliest Stages
The investigational blood test detected stage 1 and 2 disease with 87% accuracy and a 3% false-positive rate in low-risk patients.
- A large, international study published in Nature Medicine found that PANXEON, a new liquid biopsy test, successfully identified stage 1 and 2 pancreatic cancer with high sensitivity and low false-positive rates.
- Researchers at City of Hope led development of the test to address a critical challenge: 90% of pancreatic cancer patients receive diagnoses only after the malignancy has already spread to advanced stages.
- Testing nearly 1,800 patients across the United States, Europe, and Asia, the study found the test correctly identified stage 1 and 2 cancer 87% of the time and detected high-grade dysplasia, or "stage 0" cancer, more than 64% of the time.
- Senior author Ajay Goel said PANXEON helps identify high-risk patients needing further evaluation, stating, "The earlier we find pancreatic cancer, the greater the chance that meaningful intervention is still possible."
- Supported by a $150 million gift to the Stephenson Global Pancreatic Cancer Research Institute, City of Hope continues advancing early detection research and moving pancreatic cancer intervention earlier in disease progression.
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cedarnews.netTumors of the pancreas are usually only recognizable when they can hardly be treated. A new blood test can help in early detection. Hope also awakens a new active ingredient. By Julia Jakob
Novel blood test could detect pancreatic cancer at its earliest stages
Researchers at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the country, led the development of a new, investigational blood test that could detect pancreatic cancer at its earliest stages, when the disease is more treatable and potentially curable.
The analysis, which is still to be tested on a large scale, detected approximately 87% of the cases in stages I and II, when this tumor still does not usually show its faceThe genetic analysis of a thousand tumors reveals the reasons why prostate cancer spreads Being able to detect cancer in its early stages with a simple blood test — known as liquid biopsies — is one of the great challenges that science faces. Although it is still far away, tha…
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