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A single skin gene helps build the body's first line of immune defense
Ben-Gurion University researchers found that ZNF750 gene controls IL-34 production, essential for Langerhans cell survival, linking skin barrier formation with immune protection.
Summary by Medical Xpress
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2 Articles
A single skin gene helps build the body's first line of immune defense
Researchers at Ben-Gurion University of the Negev (BGU) have discovered that a gene long known for shaping the skin's physical barrier also plays a crucial role in building and maintaining the skin's immune defense. The findings, published in Cell Reports, reveal a previously unknown mechanism linking skin development to immune protection—and offer new insights into inflammatory skin diseases such as psoriasis and atopic dermatitis.
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