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A Distribution-Based Metric for Quantifying Dispersibility in Dry Powder Inhalers
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A Distribution-Based Metric for Quantifying Dispersibility in Dry Powder Inhalers
Abstract Background/Objectives: Reproducible evaluation of aerosol dispersibility remains a key challenge in the development of dry powder inhalers (DPIs), where small variations in particle cohesion, morphology, or device resistance can lead to large differences in aerodynamic performance. In passive DPIs, the forces required for powder fluidization and aerosolization arise from the interaction of patient inspiratory airflow with device geometr…
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