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49ers injury report: George Kittle, Nick Bosa, and Christian McCaffrey cleared to play vs. Rams
George Kittle, Nick Bosa and Christian McCaffrey are set to play, giving San Francisco three key starters back for its season opener.
- On Friday, the San Francisco 49ers open their 2026 season against the Los Angeles Rams at the Melbourne Cricket Ground in Australia, with stars Nick Bosa, George Kittle, and Christian McCaffrey all expected to play.
- Bosa returns from an ACL tear suffered in September 2025, while Kittle recovered from a torn Achilles sustained during January's NFC wild card victory against the Philadelphia Eagles.
- Despite losing defensive tackle Alfred Collins for the season to a torn patellar tendon, rookie James Thompson Jr. is active for the matchup following his hamstring injury.
- Head coach Kyle Shanahan confirmed the team will manage player workloads carefully, stating "they both look great, but we've definitely got to be smart with that."
- Los Angeles enters the prime-time contest without defensive tackle Aaron Donald, who did not travel with the team to Australia, leaving San Francisco to face a modified Rams lineup.
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Rams vs. 49ers injury report: Latest on Myles Garrett, Aaron Donald, George Kittle and more for Week 1
After the 2026 NFL season opened on Wednesday with the Seattle Seahawks defeating the New England Patriots, another mouthwatering matchup awaits on Thursday as the Los Angeles Rams take on the San Fra
Coverage Details
Total News Sources24
Leaning Left4Leaning Right1Center9Last UpdatedBias Distribution64% Center
Bias Distribution
- 64% of the sources are Center
64% Center
L 29%
C 64%
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